Background
Pam M. Van Ry is an Assistant Professor in the Department of Chemistry and Biochemistry at Brigham Young University
Pam M. Van Ry’s research interests are in uncovering mechanisms of fibrotic dieses and developing therapeutics to combat those diseases. Her work has appeared in journals including: Human Molecular Genetics, Molecular therapy, and Journal of Cell Science. She teaches both undergraduate and graduate classes in biochemistry.
Cancer Research
Over the ten years conducting research in the field of Fibrotic diseases, I continuously read articles highlighting the overlap between fibrosis and cancer metastasis. Over the years more research has established this connection and cancer metastasis is categorized as a fibrotic phase of cancer. I have applied my knowledge in the field of pulmonary fibrosis to develop a 3D lung organoid model. Our long-term goal is to identify key points of therapy in fibrotic metastatic cancers. To achieve this goal, our current research objective is to characterize the senescent cancer associated fibroblasts secretome and identify specific pathways that control metastasis.